.

Dr. Rajesh Raju

Founder & Director
Biography

Dr. Rajesh Raju earned his Ph.D. in Biotechnology from the Institute of Bioinformatics (IOB) in Bangalore, India, in collaboration with Kuvempu University, Shivamogga. He is a prominent figure in the field of molecular biology and bioinformatics, actively contributing to various research and data resource projects. He has played a pivotal role in leading IOB's endeavors in developing and analyzing signaling pathways within NetPath, a valuable resource for researchers exploring cellular signaling networks. His contributions extend to the creation of a draft map of the human proteome, a groundbreaking achievement that graced the cover of the prestigious journal Nature in May 2014. Throughout his career, Dr. Rajesh Raju has been involved in curating, reviewing, and coordinating major global biological data resources, including the Human Protein Reference Database, Plasma Proteome Database, Pancreatic Cancer Database, and Triple Negative Breast Cancer Database. His expertise has also been instrumental in the analysis of sequence variations in Primary Immunodeficiency Disorders (PID) and the development of a pioneering approach for predicting novel PID genes in collaboration with the RIKEN Centre for Allergy and Immunology in Japan. In recognition of his outstanding contributions to the scientific community, Dr. Rajesh Raju received an independent young investigator award grant from the Science and Engineering Research Board (SERB), under the Department of Science and Technology, Government of India, in 2015. He has also represented India in the Indo-Japan youth exchange program in science, fostering international collaboration and knowledge exchange. His expertise is not limited to research; he is an accomplished reviewer for numerous international journals, including Nature Communications, Proteomics, and Scientific Reports, among others. His keen insights and critical evaluations have enriched the peer-review process and advanced the quality of scientific publications. Currently, Dr. Rajesh Raju is at the forefront of establishing an Integrated Data Science Unit, a visionary initiative that aims to facilitate the analysis of biological context-dependent signatures at multiple levels, including the genome, transcriptome (mRNA, miRNA, lncRNA, etc.), metabolome, proteome, and multiPTM profiles. This unit promises to be a platform for cutting-edge research in systems biology and translational research, underlining Dr. Rajesh Raju’s commitment to advancing our understanding of complex biological systems and their relevance to human health and disease.

Dr. Rajesh Raju

Founder & Director
Research Interest/area

  • Biological signal transduction pathways
  • Genomics, transcriptomics, proteomics and metabolomics
  • PTM-omics and identification of enzyme-substrate relationships
  • Development of tools and resources for systems biology
  • Regulatory association between protein-coding and non-coding RNA Education
Education

  • Ph.D. in Biotechnology, Kuvempu University, India, 2012
  • M.Sc. in Biotechnology, Karpagam Arts and Science college, India, 2003
Positions held

  • Assistant Professor (Dec 2020 - till date), Centre for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (deemed to be University), Mangalore, Karnataka
  • DST-SERB Scientist (Dec 2015 - Jun 2019), Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram, Kerala
  • Program Scientist (May 2015 - Dec 2015), Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram, Kerala
  • Post-doctoral Fellow (May 2014 - May 2015), Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram, Kerala
  • Faculty Scientist (Feb 2012 - Apr 2014), Institute of Bioinformatics, Bangalore, Karnataka
  • Research Associate (Jul 2007 - Mar 2008), RIKEN Centre for Allergy and Immunology, RIKEN Yokohama, Japan
  • Laboratory Technologist (Jun 2004 – Jan 2005), Medical College, Thiruvananthapuram, Kerala
Honors and Awards

  • Represented India in the Indo-Japan Youth Exchange Programme in Science (2016)
  • DST-SERB Young Scientist Award, Department of Science and Technology, India
  • Research Associateship, RIKEN Centre for Allergy and Immunology, Japan
  • Senior Research Fellowship, Council of Scientific & Industrial Research, India
  • Qualified National Eligibility Test (UGC-NET) for Lectureship, University Grants Commission, India
Publications

Research papers: 71; Review articles: 1;

2024 (Number of publications - 19)

  • Banjan, B., Raju, R., Keshava Prasad, T. S., & Abhinand, C. S. (2024). Computational identification of potential bioactive compounds from Triphala against alcoholic liver injury by targeting alcohol dehydrogenase. Molecular diversity, 10.1007/s11030-024-10879-9. Advance online publication. [DOI]
  • Daniel Thomas, S., Vijayakumar, K., John, L., Krishnan, D., Rehman, N., Revikumar, A., Kandel Codi, J. A., Prasad, T. S. K., S S, V., & Raju, R. (2024). Machine Learning Strategies in MicroRNA Research: Bridging Genome to Phenome. Omics : a journal of integrative biology, 10.1089/omi.2024.0047. Advance online publication. [DOI]
  • Mahin, A., Chikmagalur Ravindra, S., Ramesh, P., Naik, P., Raju, R., Keshava Prasad, T. S., & Abhinanad, C. S. (2024). Unveiling Actin Cytoskeleton Role in Mediating Chikungunya-Associated Arthritis: An Integrative Proteome-Metabolome Study. Vector borne and zoonotic diseases (Larchmont, N.Y.), 10.1089/vbz.2024.0018. Advance online publication. [DOI]
  • Aravind, A., Nandakumar, R., Ahmed, M., Nisar, M., Palollathil, A., Kanichery, A., Sreelan, S., Sinan, K. M., Balaya, R. D. A., Vijayakumar, M., Prasad, T. S. K., & Raju, R. (2024). REMEMProt: a resource of membrane-enriched proteome profiles, their disease associations, and biomarker status. Life science alliance, 7(7), e202302443. [DOI]
  • Suchitha, G. P., Dagamajalu, S., Keshava Prasad, T. S., & Devasahayam Arokia Balaya, R. (2024). A Comprehensive Network Map of Interleukin-26 Signaling Pathway. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 10.1089/jir.2024.0026. Advance online publication. https://doi.org/10.1089/jir.2024.0026 [DOI]
  • Suchitha, G. P., Devasahayam Arokia Balaya, R., Prasad, T. S. K., & Dagamajalu, S. (2024). A signaling network map of Lipoxin (LXA4): an anti-inflammatory molecule. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 10.1007/s00011-024-01885-6. Advance online publication. [DOI]
  • Thimmappa, P. Y., Nair, A. S., D'silva, S., Aravind, A., Mallya, S., Soman, S. P., Guruprasad, K. P., Shastry, S., Raju, R., Prasad, T. S. K., & Joshi, M. B. (2024). Neutrophils display distinct post-translational modifications in response to varied pathological stimuli. International immunopharmacology, 132, 111950. Advance online publication. [DOI]
  • Vishwakarma, R., Ramakrishnan, K., & Rehman, N. (2024). Riddling Substitution of "hsa" to "has" in the Enigmatic MicroRNA Nomenclature. Omics : a journal of integrative biology, 10.1089/omi.2023.0248. Advance online publication. [DOI]
  • Sanjeev, D., George, M., John, L., Gopalakrishnan, A. P., Priyanka, P., Mendon, S., Yandigeri, T., Nisar, M., Nisar, M., Kanekar, S., Balaya, R. D. A., & Raju, R. (2024). Tyr352 as a Predominant Phosphosite in the Understudied Kinase and Molecular Target, HIPK1: Implications for Cancer Therapy. Omics : a journal of integrative biology, 10.1089/omi.2023.0244. Advance online publication. [DOI]
  • Banjan, B., Koshy, A. J., Kalath, H., John, L., Soman, S., Raju, R., & Revikumar, A. (2024). Potential protein kinase inhibitors that target G-quadruplex DNA structures in the human telomeric regions. Molecular diversity, 10.1007/s11030-023-10768-7. Advance online publication. [DOI]
  • Priyanka, P., Gopalakrishnan, A. P., Nisar, M., Shivamurthy, P. B., George, M., John, L., Sanjeev, D., Yandigeri, T., Thomas, S. D., Rafi, A., Dagamajalu, S., Velikkakath, A. K. G., Abhinand, C. S., Kanekar, S., Prasad, T. S. K., Balaya, R. D. A., & Raju, R. (2024). A global phosphosite-correlated network map of Thousand And One Kinase 1 (TAOK1). The international journal of biochemistry & cell biology, 106558. Advance online publication. https://doi.org/10.1016/j.biocel.2024.106558 [DOI]
  • Karpagavalli, K., Magdaline, J. D., Chithambarathanu, T., Vijaya, P., & Amjesh, R. (2024). Quantum chemical evaluation, ELF, LOL analysis, Fukui, herbicide-likeness and molecular docking studies of 4-methyl-phenoxyacetic acid, 4-acetyl-phenoxyacetic acid and 4-tert-butyl-phenoxyacetic acid – a comparative study. Structural Chemistry. https://doi.org/10.1007/s11224-023-02271-4 [DOI]
  • Niarakis, A., Ostaszewski, M., Mazein, A., Kuperstein, I., Kutmon, M., Gillespie, M. E., Funahashi, A., Acencio, M. L., Hemedan, A., Aichem, M., Klein, K., Czauderna, T., Burtscher, F., Yamada, T. G., Hiki, Y., Hiroi, N. F., Hu, F., Pham, N., Ehrhart, F., Willighagen, E. L., … COVID-19 Disease Map Community (2024). Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches. Frontiers in immunology, 14, 1282859. [DOI]
  • Gopal, D., Muthuraj, R., Balaya, R. D. A., Kanekar, S., Ahmed, I., & Chandrasekaran, J. (2024). Computational discovery of novel FYN kinase inhibitors: a cheminformatics and machine learning-driven approach to targeted cancer and neurodegenerative therapy. Molecular diversity, 10.1007/s11030-024-10819-7. Advance online publication. [DOI]
  • Shaji, V., Dagamajalu, S., Sanjeev, D., George, M., Kanekar, S., Prasad, G., Keshava Prasad, T. S., Raju, R., & Devasahayam Arokia Balaya, R. (2024). Deciphering the Receptor-Mediated Signaling Pathways of Interleukin-19 and Interleukin-20. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 10.1089/jir.2024.0009. Advance online publication. https://doi.org/10.1089/jir.2024.0009 [DOI]
  • Hemavathi, K. N., Skariyachan, S., Raju, R., Keshava Prasad, T. S., & Abhinand, C. S. (2024). Computational screening of potential anti-inflammatory leads from Jeevaneeya Rasayana plants targeting COX-2 and 5- LOX by molecular docking and dynamic simulation approaches. Computers in biology and medicine, 171, 108164. Advance online publication. https://doi.org/10.1016/j.compbiomed.2024.108164 [DOI]
  • Giridhara Prema, S., Chandrasekaran, J., Kanekar, S., George, M., Prasad, T. S. K., Raju, R., Dagamajalu, S., & Balaya, R. D. A. (2024). Cisplatin and Procaterol Combination in Gastric Cancer? Targeting Checkpoint Kinase 1 for Cancer Drug Discovery and Repurposing by an Integrated Computational and Experimental Approach. Omics : a journal of integrative biology, 10.1089/omi.2023.0163. Advance online publication. https://doi.org/10.1089/omi.2023.0163 [DOI]
  • Krishnan, D., Babu, S., Raju, R., Veettil, M. V., Prasad, T. S. K., & Abhinand, C. S. (2024). Epstein-Barr Virus: Human Interactome Reveals New Molecular Insights into Viral Pathogenesis for Potential Therapeutics and Antiviral Drug Discovery. Omics : a journal of integrative biology, 10.1089/omi.2023.0241. Advance online publication. https://doi.org/10.1089/omi.2023.0241 [DOI]
  • Mahin, A., Soman, S. P., Modi, P. K., Raju, R., Keshava Prasad, T. S., & Abhinand, C. S. (2024). Meta-analysis of the serum/plasma proteome identifies significant associations between COVID-19 with Alzheimer's/Parkinson's diseases. Journal of neurovirology, 10.1007/s13365-023-01191-7. Advance online publication. [DOI]

2023 (Number of publications - 19)

  • Ramakrishnan, K., Babu, S., Shaji, V., Soman, S., Leelamma, A., Rehman, N., & Raju, R. (2023). Hepatitis B Virus Modulated Transcriptional Regulatory Map of Hepatic Cellular MicroRNAs. Omics : a journal of integrative biology, 27(12), 581–597. [DOI]
  • Varghese, B., Babu, S., Jala, A., Das, P., Raju, R., Borkar, R. M., & Adela, R. (2023). Integrative Placental Multi-Omics Analysis Reveals Perturbed Pathways and Potential Prognostic Biomarkers in Gestational Hypertension. Archives of medical research, 55(1), 102909. Advance online publication. [DOI]
  • Devasahayam Arokia Balaya, R., Chandrasekaran, J., Kanekar, S., Kumar Modi, P., Dagamajalu, S., Gopinathan, K., Raju, R., & Prasad, T. S. K. (2023). Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) inhibitors: a novel approach in small molecule discovery. Journal of biomolecular structure & dynamics, 1–11. Advance online publication. [DOI]
  • Chatterjee, O., Gopalakrishnan, L., Pullimamidi, D., Raj, C., Yelamanchi, S., Gangadharappa, B. S., Nair, B., Mahadevan, A., Raju, R., & Keshava Prasad, T. S. (2023). A molecular network map of orexin-orexin receptor signaling system. Journal of cell communication and signaling, 17(1), 217–227. [DOI]
  • Revikumar A. (2023). An Omics Strategy for Translational Bioinformatics and Rapid COVID-19 Drug Repurposing. Omics : a journal of integrative biology, 27(3), 109–115. [DOI]
  • Sankaran, D., Amjesh, R., Paul, A. M., George, B., Kala, R., Saini, S., & Kumar, R. (2023). Hyperactivation of p21-Activated Kinases in Human Cancer and Therapeutic Sensitivity. Biomedicines, 11(2), 462. [DOI]
  • Abhinand, C. S., Galipon, J., Mori, M., Ramesh, P., Prasad, T. S. K., Raju, R., Sudhakaran, P. R., & Tomita, M. (2023). Temporal phosphoproteomic analysis of VEGF-A signaling in HUVECs: an insight into early signaling events associated with angiogenesis. Journal of cell communication and signaling, 17(3), 1067–1079 [DOI]
  • Abhinand, C. S., Prabhakaran, A. A., Krishnamurthy, A., Raju, R., Keshava Prasad, T. S., Nair, A. S., Rajasekharan, K. N., Oommen, O. V., & Sudhakaran, P. R. (2022). SARS-CoV-2 variants infectivity prediction and therapeutic peptide design using computational approaches. Journal of biomolecular structure & dynamics, 1–12. Advance online publication. [DOI]
  • Banjan, B., Krishnan, D., Koshy, A. J., Soman, S., Leelamma, A., Raju, R., & Revikumar, A. (2023). In-silico screening and identification of potential drug-like compounds for dengue-associated thrombocytopenia from Carica papaya leaf extracts. Journal of biomolecular structure & dynamics, 1–19. Advance online publication. [DOI]
  • Devadasan, M. J., Ramesha, K. P., Ramesh, P., Kootimole, C. N., Jeyakumar, S., Ashwitha, A., Ammankallu, S., Rai, A. B., Kumaresan, A., Vedamurthy, V. G., Raju, R., Das, D. N., Kataktalware, M. A., & Prasad, T. S. K. (2023). Exploring molecular dynamic indicators associated with reproductive performance of Bos indicus cattle in blood plasma samples through data-independent acquisition mass spectrometry. Journal of proteomics, 285, 104950. [DOI]
  • Kalath, H., Koshy, A. J., Banjan, B., Soman, S., Hosadevasthana, G., Raju, R., Rehman, N., & Revikumar, A. (2023). In-silico studies of Brassica oleracea active compounds and their role in thyroid peroxidase activity. Journal of biomolecular structure & dynamics, 1–17. Advance online publication. [DOI]
  • Kumar, S., Balaya, R. D. A., Kanekar, S., Raju, R., Prasad, T. S. K., & Kandasamy, R. K. (2023). Computational tools for exploring peptide-membrane interactions in gram-positive bacteria. Computational and structural biotechnology journal, 21, 1995–2008. [DOI]
  • Mol, P., Balaya, R. D. A., Dagamajalu, S., Babu, S., Chandrasekaran, P., Raghavan, R., Suresh, S., Ravishankara, N., Raju, A. H., Nair, B., Modi, P. K., Mahadevan, A., Prasad, T. S. K., & Raju, R. (2023). A network map of GDNF/RET signaling pathway in physiological and pathological conditions. Journal of cell communication and signaling, 17(3), 1089–1095 [DOI]
  • Ramesh, P., Behera, S. K., Kotimoole, C. N., Mohanty, V., Raju, R., Prasad, T. S. K., & Codi, J. A. K. (2023). Mining proteomics data to extract post-translational modifications associated with gastric cancer. Amino acids, 55(8), 993–1001. [DOI]
  • Sanjeev, D., Dagamajalu, S., Shaji, V., George, M., Subbannayya, Y., Prasad, T. S. K., Raju, R., & Devasahayam Arokia Balaya, R. (2023). A network map of macrophage-stimulating protein (MSP) signaling. Journal of cell communication and signaling, 17(3), 1113–1120.[DOI]
  • Suchitha, G. P., Balaya, R. D. A., Raju, R., Keshava Prasad, T. S., & Dagamajalu, S. (2023). A network map of cytoskeleton-associated protein 4 (CKAP4) mediated signaling pathway in cancer. Journal of cell communication and signaling, 17(3), 1097–1104. [DOI]
  • Thatai, A. K. S., Ammankallu, S., Devasahayam Arokia Balaya, R., Soman, S. P., Nisar, M., Babu, S., John, L., George, A., Anto, C. K., Sanjeev, D., Kandiyil, M. K., Raj, S. S., Awasthi, K., Vinodchandra, S. S., Prasad, T. S. K., & Raju, R. (2023). VirhostlncR: A comprehensive database to explore lncRNAs and their targets in viral infections. Computers in biology and medicine, 164, 107279. [DOI]
  • Upadhyay, S. S., Devasahayam Arokia Balaya, R., Parate, S. S., Dagamajalu, S., Keshava Prasad, T. S., Shetty, R., & Raju, R. (2023). An assembly of TROP2-mediated signaling events. Journal of cell communication and signaling, 17(3), 1105–1111. [DOI]
  • Manjunath, V., Thenral, S. G., Lakshmi, B. R., Nalini, A., Bassi, A., Karthikeyan, K. P., Piyusha, K., Menon, R., Praveena, L. S., Anjanappa, R. M., Murugan, M. S., Polavarapu, K., Bardhan, M., Preethish-Kumar, v., Vengalil, S., Nashi, S., Sanga, S., Acharya, M., Raju, R., Pai, V. R., Ramprasad, V. L., & Gupta, R. (2023). Large Region of Homozygous (ROH) Identified in Indian Patients with Autosomal Recessive Limb-Girdle Muscular Dystrophy with p. Thr182Pro Variant in SGCB Gene. Human Mutation.[DOI]

2022 (Number of publications - 09)

  • Abhinand, C. S., Athira, P., Krishnamurthy, A., Raju, R., Prasad, T. S. K., Nair, A. S., Rajasekharan, K. N., Oommen, O. V. and Sudhakaran, P. R. (2022). SARS-CoV-2 variants infectivity prediction and therapeutic peptide design using computational approaches. Journal of Biomolecular Structure & Dynamics. [PubMed]
  • Abhinand, C. S., Ibrahim, J., Keshava Prasad, T. S., Raju, R., Oommen, O. V., & Nair, A. S. (2023). Molecular docking and dynamics studies for the identification of Nipah virus glycoprotein inhibitors from Indian medicinal plants. Journal of biomolecular structure & dynamics, 41(19), 9211–9218. [DOI]
  • Ramesh, P., Babu, S., Ammankallu, S., Codi, J. A. K., Prasad, T. S. K., & Raju, R. (2023). Helicobacter pylori regulated microRNA map of human gastric cells. Helicobacter, 28(1), e12941. [DOI]
  • Dagamajalu, S., Rex, D. A. B., Suchitha, G. P., Rai, A. B., Kumar, S., Joshi, S., Raju, R., & Prasad, T. S. K. (2023). A network map of discoidin domain receptor 1(DDR1)-mediated signaling in pathological conditions. Journal of cell communication and signaling, 17(3), 1081–1088. [DOI]
  • Chatterjee, O., Gopalakrishnan, L., Pullimamidi, D., Raj, C., Yelamanchi, S., Gangadharappa, B. S., Nair, B., Mahadevan, A., Raju, R., and Prasad, T.S.K. (2022). A molecular network map of orexin-orexin receptor signaling system Journal of Cell Communication and Signaling. In Press.
  • Rex, D. A. B., Dagamajalu, S., Gouda, M. M., Suchitha, G. P., Chanderasekaran, J., Raju, R., Prasad, T. S. K., & Bhandary, Y. P. (2023). A comprehensive network map of IL-17A signaling pathway. Journal of cell communication and signaling, 17(1), 209–215. [DOI]
  • Antil, N., Arefian, M., Kandiyil, M. K., Awasthi, K., Prasad, T. S. K., & Raju, R. (2022). The Core Human MicroRNAs Regulated by Toxoplasma gondii. MicroRNA (Shariqah, United Arab Emirates), 11(2), 163–174. [DOI]
  • Revikumar, A., Kashyap, V., Palollathil, A., Aravind , A., Raguraman , R., Kumar, K. M. K., Vijayakumar , M., Prasad, T. S. K. and Raju, R. (2022). Multiple G-quadruplex binding ligand induced transcriptomic map of cancer cell lines. Journal of Cell Communication and Signaling. 16, 129-135.
  • Aravind, A., Palollathil, A., D. A. B. Rex, Kumar, K. M. K., Vijayakumar, M., Shetty, R., Codi, J. A. K., Prasad, T. S. K. and Raju, R. (2022). A multi-cellular molecular signaling and functional network map of C-C Motif Chemokine Ligand 18 (CCL18): A chemokine with immunosuppressive and pro-tumor functions. Journal of Cell Communication and Signaling. 16, 293-300. [DOI]

2021 (Number of publications - 05)

  • Behera, S. K., Modi, P. K., Karthikkeyan, G., Pervaje, S. K., Pervaje, R., Raju, R., Prasad, T. S. K. and Subbannayya, Y. (2021). From LC-MS/MS metabolomics profiling of Kanchanara Guggulu to molecular docking and dynamics simulation of quercetin pentaacetate with aldose reductase. Bioinformation 17, 911-915. (* Corresponding author)
  • Gopalakrishnan, L., Chatterjee, O., Ravishankar, N., Suresh, S., Raju, R.*, Mahadevan, A. and Prasad, T. S. K.* (2021). Opioid receptors signaling network. Journal of Cell Communication and Signaling. (* Corresponding authors) [PubMed]
  • Rex, D. A. B., Dagamajalu, S.*, Raju, R.*, Kandasamy, R. K. and Prasad T. S. K.* (2021). SARS-CoV-2 signaling pathway map: A functional landscape of molecular mechanism in COVID-19. Journal of Cell Communication and Signaling. In press. (* Corresponding authors)
  • Palollathil, A., Aravind, A., Vijayakumar, M.*, Kotimoole, C. N., Mohanty, V., Behera, S. K., Kashyap, V., Mallikarjunaiah, K. K. K., Shetty, R., Codi, J. A. K., Raju, R.* and Prasad, T. S. K.* (2021). OMICs data mining for MultiPTMs in oral cancer: cellular proteome and secretome of chronic tobacco treated oral keratinocytes. OMICS: A Journal of Integrative Biology. In press. (* Corresponding authors)
  • Behera, S. K., Kasaragod, S., Karthikkeyan, G., Kotimoole, C. N., Raju, R. , Prasad, T. S. K., and Subbannayya, Y. (2021). MS2Compound: A user friendly compound identification tool for LC-MS/MS based metabolomics data. OMICS: A Journal of Integrative Biology. In press.

2020 (Number of publications - 01)

  • Dagamajalu, S., Rex, D. A. B., Gopalakrishnan, L., Karthikkeyan, G., Gurtoo, S., Modi, P. K., Mohanty, V., Mujeeburahiman, M., Soman, S., Raju, R., Tiwari, V. and Prasad, T. S. K. (2020). A network map of endothelin mediated signaling pathway. Journal of Cell Communication and Signaling. [PubMed]

2019 (Number of publications - 01)

  • Sunitha, P., Raju, R*., Sajil, C. K., Abhinand, C. S., Nair, A. S., Oommen, O. V., Sugunan, V. S. and Sudhakaran, P. R. (2019). Temporal VEGFA responsive genes in HUVECs: Gene signatures and potential ligands/receptors fine-tuning angiogenesis. Journal of Cell Communication and Signaling. [PubMed] (*Co-corresponding author)

2018 (Number of publications - 02)

  • Krug, K., Mertins, P., Zhang, B., Hornbeck, P., Raju, R., Ahmad, R., Szucs, M., Mundt, F., Forestier, D., Jane-Valbuena, J., Keshishian, H., Michael, A. G., Tamayo, P., Mesirov, J. P., Jaffe, J. D., Carr, S. A. and Mani, D. R. (2018). A curated resource for phosphosite-specific signature analysis. Molecular & Cellular Proteomics. 18(3):576-593. [PubMed]
  • Pinto, S. M., Subbannayya, Y., Rex, D. A. B., Raju, R., Chatterjee, O., Advani, J., Radhakrishnan, A., Prasad, T. S. K., Wani, M. R. and Pandey, A. (2018). A network map of IL-33 signaling pathway. Journal of Cell Communication and Signaling. 12(3):615-624. [PubMed]

2017 (Number of publications - 01)

  • Richard, V., Raju, R., Paul, A. M., Girijadevi, R., Santhoshkumar, T. R. and Pillai, M. R. (2017). Analysis of MicroRNA-mRNA Interactions in Stem-cell Enriched Fraction of Oral Squamous Cell Carcinoma. Oncology Research. 19;26(1):17-26. [PubMed]

2016 (Number of publications - 02)

  • Jayaram, S., Gupta, M. K., Raju, R., Gautam, P. and Sirdeshmukh, R. (2016). Multi-Omics Data Integration and Mapping of Altered Kinases to Pathways Reveal Gonadotropin Hormone Signaling in Glioblastoma. OMICS: A Journal of Integrative Biology. 20(12):736-746. [PubMed]
  • Abhinand, C. S., Raju, R, Soumya, S. J., Arya, P. S. and Sudhakaran, P. R. (2016). VEGF-A/VEGFR2 Signaling network in endothelial cells relevant to angiogenesis. Journal of Cell Communication and Signaling. 10(4):347-354. [PubMed]

2015 (Number of publications - 03)

  • Raju, R., Gadakh, S., Gopal, P., George, B., Advani, J., Soman, S., Prasad, T. S. K. and Girijadevi, R. (2015). Differential ligand-signaling network of CCL19/CCL21-CCR7 system. Database (Oxford). 2015. pii: bav106. [PubMed]
  • Sharma, J., Balakrishnan, L., Datta, K. K., Sahasrabuddhe, N. A., Khan, A. A., Sahu, A., Singhal, A., Getnet, D., Raju, R., Chatterjee, A., Gowda, H., Prasad, T. S. K, Shankar, S. and Pandey, A. (2015). A knowledgebase resource for interleukin-17 family mediated signaling. Journal of Cell Communication and Signaling. 9(3):291-6.[PubMed]
  • Mitchell, C. J., Getnet, D., Kim, M. S., Manda, S. S., Kumar, P., Huang, T. C., Pinto, S. M., Nirujogi, R. S., Iwasaki, M., Shaw, P. G., Wu, X., Zhong, J., Chaerkady, R., Marimuthu, A., Muthusamy, B., Sahasrabuddhe, N. A., Raju, R., Bowman, C., Danilova, L., Cutler, J., Kelkar, D. S., Drake, C. G., Prasad, T. S. K, Marchionni, L., Murakami, P. N., Scott, A. F., Shi, L., Thierry-Mieg, D., Irizarry, R., Cope, L., Ishihama, Y., Wang, C., Gowda, H. and Pandey, A. (2015). A multi-omic analysis of human naïve CD4+ T cells. BMC Systems Biology. 6;9:75. [PubMed]

2014 (Number of publications - 12)

  • Raju, R., Paul, A. M., Vivekanand, A., George, B., Lekshmi, R., Vinaykumar, M., Reshmi, G. and Pillai, M. R. (2014). The Triple-Negative Breast Cancer Database: an omics platform for reference, integration and analysis of triple-negative breast cancer data. Breast Cancer Research16:490. [PubMed]
  • Wu, X., Renuse, S., Sahasrabuddhe, N. A., Zahari, M. A., Chaerkady, R., Kim, M., Nirujogi, R. S., Mohseni, M., Kumar, P., Raju, R., Zhong, J., Yang, J., Jung, J., Neiswinger, J., Newman, R., Qian, J., Zhu, H., Vogelstein, B., Park, B. H. and Pandey, A. (2014). Activation of diverse signaling pathways by oncogenic PIK3CA mutations. Nature Communications. 5, 4961. [PubMed]
  • Kim, M. S., Pinto, S. M., Getnet, D., Nirujogi, R. S., Manda, S. S., Chaerkady, R., Madugundu, A. K., Kelkar, D. S., Isserlin, R., Jain, S., Thomas, J. K., Muthusamy, B., Leal-Rojas, P., Kumar, P., Sahasrabuddhe, N. A., Balakrishnan, L., Advani, J., George, B., Renuse, S., Selvan, L. D. N., Patil, A. H., Nanjappa, V., Radhakrishnan, A., Prasad, S., Subbannayya, T., Raju, R., Kumar, M., Sreenivasamurthy, S. K., Marimuthu, A., Sathe, G. J., Chavan, S., Datta, K. K., Subbannayya, Y., Sahu, A., Yelamanchi, S. D., Jayaram, S., Rajagopalan, P., Sharma, J., Murthy, K. R., Syed, N., Goel, R., Khan, A. A., Ahmad, S., Dey, G., Mudgal, K., Chatterjee, A., Huang, T. C., Zhong, J., Wu, X., Shaw, P. G., Freed, D., Zahari, M. S., Mukherjee, K. K., Shankar, S., Mahadevan, A., Lam, H., Mitchell, C. J., Shankar, S. K., Satishchandra, P., Schroeder, J. T., Sirdeshmukh, R., Maitra, A., Leach, S. D., Drake, C. G., Halushka, M. K., Prasad, T. S. K., Hruban, R. H., Kerr, C. L., Bader, G. D., Iacobuzio-Donahue, C. A., Gowda, H. and Pandey, A. (2014). A draft map of the human proteome. Nature. 509, 575-581.[PubMed]
  • Khan, A., Sandhya, V. K., Singh, P., Parthasarathy, D., Kumar, A., Advani, J., Gattu, R., Ranjit, D.V., Vaidyanathan, R., Prasad, T. S. K., Gabhann, F. M., Pandey, A., *Raju, R. and *Gowda, H. (2014). Signaling network map of endothelial TEK tyrosine kinase. Journal of Signal Transduction. 2014, 172036. [PubMed] (*Corresponding author)
  • Thomas J. K., Kim, M., Balakrishnan, L., Nanjappa, V., Raju, R., Marimuthu, A., Radhakrishnan, R., Muthusamy, B., Khan, A. A., Sakamuri, S., Tankala, S. G., Nair, B., Sirdeshmukh, R., Chatterjee, A., Prasad, T. S. K., Maitra, A., Gowda, H., Hruban, R. H. and Pandey, A. (2014). Pancreatic Cancer Database: An integrative resource for pancreatic cancer. Cancer Biology & Therapy. 19;15(8). [PubMed]
  • Pawar, H., Renuse, S., Khobragade, S. N., Chavan, S., Sathe, G., Kumar, P., Mahale, K. N., Gore, K., Raju, R., Prasad, T. S. K., Harsha, H. C., Patole, M. S. and Pandey, A (2014). Neglected tropical diseases and omics science: Proteogenomics analysis of the promastigote stage of Leishmania major parasite. OMICS: A Journal of Integrative Biology. 18:499-512. [PubMed]
  • *Raju, R., Palapetta, S. M., Sandhya, V. K., Sahu, A., Balakrishnan, L., Advani, J., George, B., Kini, K. R., Prakash, H. S., Prasad, T. S. K., Chang, Y., Chen, L., Pandey, A. and *Gowda H. (2014). A network map of FGF-1/FGFR signaling system. Journal of Signal Transduction. 2014:962962 [PubMed] (*Co-*Corresponding author)
  • Subbannayya, Y., Anuja, A., Ojha, U. K., Nanjappa, V., Advani, J., Sonawane, A., Subramanian, D., Pandey, A., Prasad, T. S. K. and *Raju, R. (2014). A network map of Gastrin signaling pathway. Journal of Cell Communication and Signaling. 8(2):165-70. [PubMed] (*Corresponding author)
  • Zhong, J., Sharma, J., Raju, R., Palapetta, S. M., Prasad, T. S. K., Huang, T. C., Yoda, A., Tyner, J. W., van Bodegom, D., Weinstock, D. M., Ziegler, S. F. and Pandey, A. (2014). TSLP signaling pathway map: A platform for analysis of TSLP mediated signaling. Database. 2014:bau007. [PubMed]
  • Balakrishnan, L., Bhattacharjee, M., Nirujogi, R. S., Renuse, S., Subbannayya, Y., Marimuthu, A., Srikanth, S. M., Raju, R., Dhillon, M., Kaur, N., Jois, R., Ramachandra, Y. L., Prasad, T. S. K., Mohan, S., Harsha, H. C., Shankar, S. and Pandey, A. (2014). Differential proteomic analysis of synovial fluid from rheumatoid arthritis and osteoarthritis patients. Clinical Proteomics. 11(1):1. [PubMed] (*Co-*Corresponding author)
  • Balakrishnan, L., Nirujogi, R. S., Bhattacharjee, M., Srikanth, M. S., Renuse, S., Kelkar, D. S., Subbannayya, Y., Raju, R., Goel, R., Thomas, J. K., Kaur, N., Dhillon, M., Tankala, S. G., Jois, R., Ramachandra, Y. L., Prasad, T. S. K., Mohan, S. S., Harsha, H. C., Shankar, S. and Pandey, A. (2014). Proteomic analysis of human osteoarthritis synovial fluid. Clinical Proteomics. 11(1):6. [PubMed] (*Co-*Corresponding author)
  • Nanjappa, V., Thomas, J. K., Marimuthu, A., Muthusamy, B., Radhakrishnan, A., Sharma, A., Khan, A. A., Balakrishnan, L., Sahasrabuddhe, N. A., Jhaveri, B. N., Sheth, K. V., Khatana, R. K., Shaw, P. G., Srikanth, S. M., Mathur, P. P., Subramanian, S., Nagaraja, D., Christopher, R., Mathivanan, S., Raju, R., Sirdeshmukh, R., Chatterjee, A., Simpson, R. J., Harsha H. C., Pandey, A. and Prasad T. S. K. (2014). Plasma Proteome Database as a resource for proteomic research- 2014 Update. Nucleic Acids Research. 42(1):D959-965. [PubMed]

2013 (Number of publications - 04)

  • *Sandhya, V. K., *Raju, R., Verma, R., Advani, J., Sharma, R., Radhakrishnan, A., Nanjappa, V., Narayana, J., Somani, B. L., Mukherjee, K. K., Pandey, A., Christopher, R. and Prasad, T. S. K. (2013). A network map of BDNF/TRKB and BDNF/p75NTR signaling system. Journal of Cell Communication and Signaling. 7(4):301-307. [PubMed]
  • Balakrishnan, L., Soman, S., Patil, Y. B., Advani, J., Thomas, J. K., Venkatesh, D. D., Urmila, K. K., Harsha, H. C., Prasad, T. S. K., Raju, R., Pandey, A., Dimitriadis, E. and Chatterjee, A. (2013). IL-11/IL11RA receptor mediated signaling: a web accessible knowledgebase. Cell Communication and Adhesion. 20(3-4):81-86.[PubMed]
  • Subbannayya, T., Balakrishnan, L., Sudarshan, G., Advani, J., Kumar, S., Mahmood, R., Nair, B., Sirdeshmukh, R., Mukherjee, K. K., Umathe, S. N., Raju, R. and Prasad, T. S. K. (2013). An integrated map of corticotropin-releasing hormone signaling pathway. Journal of Cell Communication and Signaling. 7(4):295-300 .[PubMed]
  • *Soman, S., *Raju, R., Sandhya, V. K., Advani, J., Khan, A. A., Harsha, H. C., Sudhakaran, P. R., Pandey, A. and Adishesha, P. K. (2013). A multicellular signal transduction network of AGE/RAGE signaling. Journal of Cell Communication and Signaling. 7(1), 19-23.[PubMed]

2012 (Number of publications - 05)

  • Dey, G., Radhakrishnan, A., Syed, N., Thomas, J. K., Nadig, A., Srikumar, K., Mathur, P. P., Pandey, A., Lin, S. K., Raju, R. and Prasad, T. S. K*. (2012). Signaling network of Oncostatin M pathway. Journal of Cell Communication and Signaling.7, 103-108. [PubMed]
  • Kumar, G. S. S., Venugopal, A. K., Kashyap, M. K., Raju, R., Marimuthu, A., Palapetta, S. M., Pandey, A., Mahadevan, A. and Shankar, S. K. (2012). Gene expression profiling of tuberculous meningitis co-infected with HIV. Journal of Proteomics and Bioinformatics. 5, 235-244. [PubMed]
  • Renuse, S., Harsha, H. C., Kumar, P., Acharya, P. K., Sharma, J., Kumar, G. S., Goel, R., Raju, R., Prasad, T. S. K., Slotta, T. and Pandey, A. (2012). Proteomic analysis of an unsequenced plant-Mangifera indica. Journal of Proteomics. 75, 5793-96.[PubMed]
  • Bhattacharjee, M., Raju, R., Radhakrishnan, A., Nanjappa, V., Muthusamy, B., Singh, K., Kuppusaami, D., Lingala, B. T., Pan, A., Mathur, P. P., Harsha, H. C., Prasad, T. S. K., Atkins, G. J., Pandey, A. and Chatterjee, A. (2012). A bioinformatics resource for TWEAK-Fn14 signaling pathway. Journal of Signal Transduction. 2012; 2012:376470.[PubMed]
  • Radhakrishnan, A., Raju, R., Tuladhar, N., Subbannayya, T., Thomas, J. K., Goel, R., Telikicherla, D., Rahiman, B. A., Venkatesh, D. D., Urmila, K. K., Harsha, H. C., Mathur, P. P., Prasad, T. S. K., Pandey, A., Shemanko, C. and Chatterjee, A. (2012). A pathway map of prolactin signaling. Journal of Cell Communication and Signaling. 6(3), 169-173.[PubMed]

2011 (Number of publications - 05)

  • Telikicherla, D., Ambekar, A., Palapetta, S. M., Raju, R., Sharma, J., Prasad, T. S. K., Mohan, S. S., Mukherjee, S. and Pandey, A. (2011). A comprehensive curated resource for Follicle Stimulating Hormone signaling. BMC Research Notes. 4, 408. [PubMed]
  • Goel, R., Raju, R., Maharudraiah, J., Kumar, G. S. S., Ghosh, K., Kumar, A., Lashmi, P. T., Sharma, J., Sharma, R., Balakrishnan, L., Pan, A., Christopher, R., Krishna, V., Mohan, S. S., Harsha, H. C., Mathur, P. P., Pandey, A. and Prasad, T. S. K. (2011). A signaling network of thyroid-stimulating hormone. Journal of Proteomics and Bioinformatics. 4, 238-241. [PubMed]
  • Nanjappa, V., Raju, R., Muthusamy, B., Thomas, J. K., Nidhina, P. A. H., Harsha, H. C., Pandey, A., Anilkumar G. and Prasad, T. S. K. (2011). A comprehensive curated reaction map of leptin signaling pathway. Journal of Proteomics and Bioinformatics. 4, 184-189.
  • Raju, R., Balakrishnan, L., Nanjappa, V., Bhattacharjee, M., Getnet, D., Muthusamy, B., Thomas, J. K., Sharma, J., Rahiman, B. A., Harsha, H. C., Shankar, S., Prasad, T. S. K., Mohan, S. S., Bader, G. D., Wani, M. R. and Pandey, A. (2011). A comprehensive manually curated reaction map of RANKL/RANK signaling pathway. Database. 2110:bar021.[PubMed]
  • Raju, R., Nanjappa, V., Balakrishnan, L., Radhakrishnan, A., Thomas, J. K., Sharma, J., Tian, M., Palapetta, S. M., Subbannayya, T., Sekhar, N. R., Muthusamy, B., Subbannayya, Y., Telikicherla, D., Kumar, G. S. S., Marimuthu, A., Prasad, T. S. K., Harsha, H. C., Rahiman, B. A., Ohara, O., Bader, G. D., Mohan, S. S., Schiemann, W. P. and Pandey, A. (2011). NetSlim: High-confidence curated signaling maps. Database. 2011:bar032.[PubMed]

2010 (Number of publications - 03)

  • Kandasamy, K*., Mohan, S. S*., Raju, R., Keerthikumar, S., Kumar, G. S. S., Venugopal, A. K., Telikicherla, D., Navarro, J. D., Mathivanan, S., Pecquet, C., Gollapudi, S. K., Tattikota, S. G., Mohan, S., Padhukasahasram, H., Subbannayya, Y., Goel, R., Jacob, H. K. C., Zhong, J., Sekhar, R., Nanjappa, V., Balakrishnan, L., Subbaiah, R., Ramachandra, Y. L., Rahiman, B. A., Prasad, T. S. K., Lin, J., Houtman, J. C. D., Desiderio, S., Renauld, J., Constantinescu, S. N., Ohara, O., Hirano, T., Kubo, M., Singh, S., Khatri, P., Draghici, S., Bader, G. D., Sander, C., Leonard, W. J. and Pandey, A. (2010) NetPath: A public resource of curated signal transduction pathways. Genome Biology. 11, R3. [PubMed]
  • Hijikata, A., Raju, R., Keerthikumar, S., Ramabadran, S., Balakrishnan, L., Ramadoss, S. K., Pandey, A., Mohan, S. and Ohara, O. (2010). Mutation@ A Glance: An integrative web application for analyzing mutations from human genetic diseases. DNA Research. 17, 197-208[PubMed]
  • Kandasamy, K., Mohan, S. S., Raju, R., Keerthikumar, S., Kumar, G. S. S., Venugopal, A. K., Telikicherla, D., Navarro, J. D., Mathivanan, S., Pecquet, C., Gollapudi, S. K., Tattikota, S. G., Mohan, S., Padhukasahasram, H., Subbannayya, Y., Goel, R., Jacob, H. K. C., Zhong, J., Sekhar, R., Nanjappa, V., Balakrishnan, L., Subbaiah, R., Rahiman, B. A., Prasad, T. S. K., Lin, J., Houtman, J. C. D., Desiderio, S., Renauld, J., Constantinescu, S. N., Ohara, O., Hirano, T., Kubo, M., Singh, S., Khatri, P., Draghici, S., Bader, G. D., Sander, C., Leonard, W. J. and Pandey, A. (2010). NetPath: A public resource of curated signal transduction pathways. Genome Biology. 11:R3[PubMed]

2009 (Number of publications - 04)

  • Kandasamy, K., Keerthikumar, S., Raju, R., Prasad, T. S. K., Ramachandra, Y. L., Mohan, S. and Pandey, A. (2009). PathBuilder - open source software for annotating and developing pathway resources. Bioinformatics. 25, 2860-2862 [PubMed]
  • Keerthikumar, S., Bhadra, S., Kandasamy, K., Raju, R., Bhattacharyya, C., Imai, K., Ohara, O., Mohan, S. and Pandey, A. (2009). Prediction of candidate primary immunodeficiency disease genes using a support vector machine learning approach. DNA Research.16, 345-351.[PubMed]
  • Keerthikumar, S., Raju, R., Kandasamy, K., Hijikata, A., Ramabadran, S., Balakrishnan, L., Ahmed, M., Rani, S., Selvan, L. N., Somanathan, D. S., Bhattacharjee, M., Gollapudi, S., Ramachandra, Y. L., Bhadra, S., Bhattacharyya, C., Imai, K., Nonoyama, S., Kanegane, H., Miyawaki, T., Pandey, A., Ohara, O. and Mohan, S. (2009). RAPID: Resource of Asian Primary Immunodeficiency Diseases. Nucleic Acids Research. 37, D86.[PubMed]
  • Prasad, T. S. K., Goel, R., Kandasamy, K., Keerthikumar, S., Kumar, S., Mathivanan, S., Telikicherla, D., Raju, R., Shafreen, B., Venugopal, A., Balakrishnan, L., Marimuthu, A., Banerjee, S., Somanathan, D. S., Sebastian, A., Rani, S., Ray, S., Kishore, C. J. H., Kanth, S., Ahmed, M., Kashyap, M., Mahmood, R., Ramachandra, Y. L., Krishna, V., Rahiman, A. B., Mohan, S., Ranganathan, P., Ramabadran, S., Chaerkady, R. and Pandey, A. (2009). Human Protein Reference Database - 2009 update. Nucleic Acids Research. 37, D767-D772.[PubMed]

Associations


  • Reviewer - Nature Communications,Proteomics, Database, DNA Research, Scientific Reports, Journal of Proteomics in Bioinformatics